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Humira
Humira (Adalimumab) is an immunosuppresant, approved by the FDA for the treatment of Crohn's Disease, rheumatoid arthritis, and juvenile arthritis. It is administered through a subcutaneous injection.
The most common side effects of Humira are dry cough, fever, weight loss, fever with chills, body aches, flu symptoms. Patients taking Humira are at increased risk for serious adverse effects, including serious infections that can lead to hospitalization or death. Because Humira affects the immune system, it can lower the body's ability to fight infections, such as tuberculosis and other opportunistic infections. Humira is a blocker of TNF (tumor necrosis factor) and may cause lymphomas (a form of cancer) and other malignancies.
Recently, Humira was given a Black Box Label Warning by the FDA. The Black Box Warning is the strongest warning label a drug can have applied to it. Drugs that carry a high risk of serious side effects or potentially deadly adverse reactions are given this warning. This label is given only after medical studies have indicated that there are serious risks associated with the side effects of the medication.
Fast Facts
| Name: | Humira |
| Generic: | Adalimumab |
| Manufacturer: | Abbott Laboratories |
| Date approved: | 2002 |
| Status: | Prescription Only - Black Box Warning Label |
| Approved uses: | Treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, moderate to severe chronic psoriasis and juvenile idiopathic arthritis. |
| Off-Label uses: | None |
| Side effects: | Feeling short of breath, even with mild exertion; swelling of your ankles or feet; red, purple, or scaly skin rash, hair loss, joint or muscle pain, mouth sores; confusion, seizure (convulsions); pain or burning when you urinate; numbness or tingly feeling, weakness in your legs; or jaundice (yellowing of the skin or eyes). Potentially Deadly Serious Fungal Infection has been reported recently by the FDA. |
| Related topics: | Cimzia, Enbrel, Remicade |






